<img height="189" width="230" alt="Dr. Beng Guat Ooi" src="http://www.mtsu.edu/chemistry/images/ooi.jpg" align="right" /><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;"><strong>CONTACT INFO:</strong><br /><br /> <span style="color:#333333;"><strong>E-mail:</strong></span> <a href="mailto:bgooi@mtsu.edu">bgooi@mtsu.edu</a></span><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;"><br /> <strong><span style="color:#333333;">Phone:</span></strong> (615) 898-2076<br /> <span style="color:#333333;"><strong>Office:</strong></span> Davis Science Bldg. 223<br /> <strong><span style="color:#333333;">P.O. Box</span></strong>: 45</span>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;"><strong>EDUCATION/INTERESTS:</strong><br /><br /> (1999) Ph.D., Monash University, Victoria, Australia (1987); Postdoctoral research at University of Georgia (1987-1989); Baylor College of Medicine, (1989-1990)</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;"><strong>CURRENT RESPONSIBILITIES:</strong></span></p>
<ul>
<li><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">Teach CHEM 1020 (Introductory Chemistry), CHEM 3530 (Biochemistry) and PSCI 1030 (Physical Science).</span></li>
<li><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">Coordinate the Biochemistry lab.</span></li>
<li><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">Coordinate the Pre-Dental Hygiene program as well as serve as advisor to Pre-Dental Hygiene students and the Delta Delta Sigma (the MTSU Chapter of American Student Dental Association).</span></li>
<li><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">Serve on the advisory board for Expanding Your Horizons in Science and Mathematics (EYH) for young women in grades 5-8.</span></li>
<li><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">Direct graduate and undergraduate research</span></li>
<li><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">Serve on the Chemistry Departmental Social Committee</span></li>
<li><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">Serve on the Committee for Instructional Media Resources Circulation Policy</span></li>
</ul>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;"><strong>RESEARCH INTERESTS:</strong></span></p>
<ul>
<li><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">Study of cigarette smoke mutagenicity via the analysis of DNA adducts resulting from tobacco toxicants</span></li>
<li><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">Investigation of the influence of yeast enzymes on wine composition and the transformation of anthocyanins during wine aging</span></li>
<li><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">Determining the relationships of wine and non-wine yeast strains by DNA sequence analysis of the rDNA genes and interspacer regions</span></li>
<li><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">Comparison of the fermentation by-products of wine and non-wine yeast</span></li>
<li><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">Study the effects of different isomeric forms of 2,3-butanediol on the quality of wine</span></li>
<li><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">Study the inhibitory effects of xylitol and other polyols on the growth of cavities causing bacteria, <em>Streptococcus mutans</em></span></li>
<li><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">Development of methods for the analysis of yeast metabolites produced by the transformation of phenanthrene</span></li>
<li><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">Studying the effects of glucose on the yield of xylitol produced from biomass-derived products by yeast<br /></span></li>
</ul>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;"><strong>SELECTED PUBLICATIONS:</strong></span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">BB. G. Ooi. “Application of Commercial and Web-Based Software Programs for DNA Sequence Analysis in Undergraduate Biochemistry Laboratory”. Chem. Educator, 10, 1-4, 2005.</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">Ngee-Sing Chong, Omobola Oladipupo, Vichuda Hunter, Beng-Guat Ooi. “Application of the AMDIS Mass Spectral Deconvolution Algorithm for the Characterization of Cigarette Smoke”. Proceedings of the 52nd ASMS Conference on Mass Spectrometry and Allied Topics, ThPD 059 (July 23, 2004).</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">B. G. Ooi. “DNA Amplification by PCR and Analysis by Gel Electrophoresis – An Undergraduate Biochemistry Experiment”. Chem. Educator, 9, 97-101, 2004.</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">B. G. Ooi, A. M. Mulisa, H. Y. Kim, & N. S. Chong. “Methods development for the detection of trace metabolites from biotransformation of polycyclic aromatic hydrocarbons by yeast”. J. Tenn. Acad. Sci., 78 (3), 65-75, 2003.</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">B. G. Ooi, T. T. B. Le, & B. M. Markuszewski. “The effects of glucose on the yeast conversion of xylose into xylitol by <em>C. guilliermondii</em> and <em>C. tropicalis</em>”. Elec. J. Env. Agri. Food Chem., 1(3), 2002.</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">B. G. Ooi & L. K. Miller. "The Influence of antisense RNA on transcription mapping of the 5' terminus of a baculovirus RNA”. Journal of General Virology, 72, 527- 534 (1991).</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">X. Wang, B. G. Ooi & L. K. Miller. "Baculovirus vectors for multiple gene expression and for occluded virus production". Gene, 100, 131-137 (1991).</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">J. R. Lupski, Y. H. Zhang, M. Rieger, M. Minter, B. Hsu, B. G. Ooi, T. Koeuth & E. R. B. McCabe. "Mutational analysis of the <em>Escherichia coli</em> glpFK region with Tn5 mutagenesis and the polymerase chain reaction". Journal of Bacteriology, 172, 6129-6134 (1990).</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">B. G. Ooi & L. K. Miller. "Transcription of the Baculovirus polyhedrin gene reduces the levels of an antisense transcription initiated downstream". Journal of Virology, 64, 3126-3129 (1990).</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">B. G. Ooi, C. Rankin & L. K. Miller. "Downstream sequence augment transcription from the essential initiation site of a baculovirus polyhedrin gene". Journal of Molecular Biology, 210, 721-736 (1989).</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">C. Rankin, B. G. Ooi & L. K. Miller. "Eight base pairs encompassing the transcription start point are the major determinant for baculovirus polyhedrin gene expression". Gene, 70, 39-49 (1988).</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">B. G. Ooi & L. K. Miller. "Regulation of host RNA levels during baculovirus infection". Virology, 166, 515-523 (1988).</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">B. G. Ooi, H. B. Lukins, A. W. Linnane & P. Nagley. "Biogenesis of mitochondrial 66. A mutation in the 5'-untranslated region of yeast mitochondrial <em>oli1</em> mRNA leading to impairment in translation of subunit 9 of the mitochondrial ATPase complex". Nucleic Acids Research, 15, 1965-1977 (1987).</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">B. G. Ooi & P. Nagley. "The oli gene and flanking sequences in mitochondrial DNA of <em>Saccharomyces cerevisiae</em>: The complete nucleotide sequence of a 1.35 kilobase petite mitochondrial DNA genome covering the oli1 gene". Current Genetics, 10, 713-723 (1986).</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">P. Nagley, R. M. Hall & B. G. Ooi. "Amino acid substitutions in mitochondrial ATPase subunit 9 of <em>Saccharomyces cerevisiae</em> leading to oligomycin or venturicidin resistance". FEBS Letters, 195, 159-163 (1986).</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">A. W. Linnane, H. B. Lukins, P. Nagley, S. Marzuki, R. G. Hadikusumo, M. J. B. Jean-Francois, U. P. John, B. G. Ooi, L. C. Watkins, T. A. Willson, J. Wright & S. Meltzer. "Assembly of the yeast mitochondrial H+-ATPase: correlative studies involving gene sequencing and immunochemical probes of assembly". In Achievements and Perspectives in Mitochondrial Research, Volume I: Bioenergetics, (F. Palmieri, ed.), Elsevier/ North Holland Biomedical Press, Amsterdam, 211-222 (1985).</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">B. G. Ooi, C. E. Novitski & P. Nagley. "DNA sequence analysis of the oli1 gene reveals amino acid changes in mitochondrial ATPase subunit 9 from oligomycin resistant mutants of <em>Saccharomyces cerevisiae</em>". European Journal of Biochemistry, 152, 709-714 (1985).</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">B. G. Ooi, G. L. McMullen, A. W. Linnane, P. Nagley & C. E. Novitski. "Biogenesis of mitochondrial 62. DNA sequence analysis of mit- mutations in the mitochondrial oli1 gene coding for mitochondrial ATPase subunit 9 in <em>Saccharomyces cerevisiae</em>". Nucleic Acids Research, 13, 1327-1339 (1985).</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">I. G. Macreadie, C. E. Novitski, R. J. Maxwell, U. John, B. G. Ooi, G. L. McMullen, H.B. Lukins, A. W. Linnane & P. Nagley. "Biogenesis of mitochondrial 59. The mitochondrial ATPase subunit 8 in <em>Saccharomyces cerevisiae</em>". Nucleic Acids Research, 11, 4435-4451 (1983).</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;"><strong>PRESENTATIONS: 4 international, 1 regional and 13 local</strong></span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">Rachel E. Thornell and Beng Guat Ooi. “The Sugar that Exhibits Dental Health Benefits” The 11 th Annual Undergraduate Research Symposium of the College of Basic And Applied Sciences. (April 15, 2005)</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">S. B. Naquin, Z. T. Frensley, N. S. Chong & B. G. Ooi. “A Study of Bidi Cigarette Smoke on <em>Salmonella typhimurium</em> strains TA97a and TA98” SCHOLAR’S DAY 2004: A University-Wide Showcase of Research, Scholarship, Creativity, and Public Service. (October 22, 2004)</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">Ngee-Sing Chong, Omobola Oladipupo, Vichuda Hunter, Beng-Guat Ooi. “Application of the AMDIS Mass Spectral Deconvolution Algorithm for the Characterization of Cigarette Smoke” 52nd American Society of Mass Spectrometry Conference in Nashville, TN (May 27, 2004)</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">Rachel E. Thornell and Beng Guat Ooi. “The Sugar that Exhibits Dental Health Benefits” The Golden Goggle Lecture & Research Open House (April 27, 2004)</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">S. B. Naquin, Z. T. Frensley, N. S. Chong & B. G. Ooi. “A Study of Bidi Cigarette Smoke on <em>Salmonella typhimurium</em> strains TA97a and TA98”, 2003 Southeast Regional ACS meeting in Atlanta, GA (November 16-19, 2003)</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">S. B. Naquin, Z. T. Frensley, N. S. Chong & B. G. Ooi. “A Study of Bidi Cigarette Smoke on <em>Salmonella typhimurium</em> strains TA97a and TA98”, Tennessee Academy of Science 113th meeting in conjuction with the Tennessee Science Teachers Association in Flanklin, TN (November 13-15, 2003)</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">B. G. Ooi, T. T. B Le., & B. M. Markuszewski. “The effects of glucose on the yeast conversion of xylose into xylitol by <em>C. guilliermondii</em> and <em>C. tropicalis</em>”, The University-wide showcase for Faculty Research and Creativity (May 2, 2003)</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">B. G. Ooi, T. T. B Le., & B. M. Markuszewski. “The effects of glucose on the yeast conversion of xylose into xylitol by <em>C. guilliermondii</em> and <em>C. tropicalis</em>”, The Golden Goggle Lecture & Research Open House (April 24, 2003)</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">B. G. Ooi, T. T. B Le., & B. M. Markuszewski. “The effects of glucose on the yeast conversion of xylose into xylitol by <em>C. guilliermondii</em> and <em>C. tropicalis</em>”, Pittsburgh Conference (March, 2003)</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">N. S. Chong, H. Y. Kim, A. M. Mulisa, and B. G. Ooi, “Methods Development for the Detection of Trace Metabolites from the Biodegradation of Polycyclic Aromatic Hydrocarbons by Yeasts”, Pittsburgh Conference (March, 2003)<br /><br /> H. Y. Kim, N.S. Chong, and B.G. Ooi. “Methods Development for the Detection of Trace Metabolites from the Biodegradation of Polycyclic Aromatic Hydrocarbons by Yeasts”. Third MTSU University-wide Faculty Research Symposium, (April 25, 2002)</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">B. M. Bednarz and B.G. Ooi. “ Relationships between Wine and Non-Wine Yeast Strains Based on Restriction Enzyme Analyses of Genomic and mtDNA”. The Golden Goggle Lecture & Research Open House (April 16, 2002)</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">H. Y. Kim, N.S. Chong, and B.G. Ooi. “Methods Development for the Detection of Trace Metabolites from the Biodegradation of Polycyclic Aromatic Hydrocarbons by Yeasts”. Second Joint Meeting of Tennessee Academy of Science and the Kentucky Academy of Science, (November 8-10, 2001).</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">A. M. Mulisa, B.G. Ooi & N. S. Chong. “Chromatographic Characterization of Metabolites from the Biotransformation of Polycyclic Aromatic Hydrocarbons by <em>C. tropicalis</em> CP1-1”. The Second MTSU University-wide Faculty Research Symposium, (April 25, 2001).</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">B. M. Bednarz & B.G. Ooi. “Comparative Studies of Wine Composition Produced by Different Yeast Strains”. The Golden Goggles Lecture/ Research Open House, (April 23, 2001). Poster was selected for first prize.</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">B. G. Ooi, N.S. Chong, and A.M. Mulisa. “Biodegradation of Polycyclic Aromatic Hydrocarbons by Yeasts”. The Golden Goggles Lecture/Research Open House, (April 23, 2001).</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">B. M. Bednarz & B.G. Ooi. “Comparative Studies of Wine Composition Produced by Different Yeast Strains”. The Sixth Annual Undergraduate Research Symposium, (April 12, 2001).</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">A. M. Mulisa, B.G. Ooi & N. S. Chong. “Chromatographic Characterization of Metabolites from the Biotransformation of Polycyclic Aromatic Hydrocarbons by <em>C. tropicalis</em>”. Pittsburgh Conference, (March, 2001).</span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;"><strong>DISSERTATION/THESIS DIRECTED:</strong></span></p>
<p><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">Master of Science Thesis entitled "Methods Development for Dectection of Trace Metabolites from the Biotransformation of Phenanthrene by Candida tropicalis 96745 CP1-1". Alex M. Mulisa</span></p>
<p><strong><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">PROFESSIONAL ORGANIZATION MEMBERSHIPS:</span></strong></p>
<ul>
<li><span style="font-family:Verdana, Arial, Helvetica, sans-serif; font-size:12px;">Tennessee Academy of Science</span></li>
</ul>