II:01:11 Animal Care and Use in Research and Teaching

I. INTRODUCTION

Middle Tennessee State University will adhere to the Laboratory Animal Welfare Act (PL 89-544 and amendments), and the NIH "Guide for the Care and Use of Laboratory Animals" in all research and teaching activities requiring animal experimentation. This includes all projects whether funded internally or externally. All research and teaching projects involving animals will be reviewed and monitored by the Institutional Animal Care and use Committee in accordance with the Laboratory Animal Welfare Act and the NIH Guide.

II. COMMITTEE MEMBERSHIP

The Committee shall consist of at least five members. The membership shall include at least:

A. One practicing scientist experienced in research involving animals.

B. One veterinarian (DVM) with training or experience in laboratory animal science and medicine and with direct or delegated program responsibility for activities involving animals at the University.

C. One member whose primary concern is in a non-scientific area (e.g. attorney, ethicist, or member of the clergy).

D. One member who is not affiliated with the University in any way other than as a member of the Committee and who is not a member of the immediate family of a person affiliated with the University.

Other members of the Committee shall be faculty members involved in research. The Director of Sponsored Programs shall serve as an ex-officio member of the committee.

Members are appointed by the President for a three-year term and may be reappointed at the discretion of the President of the University.

III. FUNCTIONS AND RESPONSIBILITIES OF THE COMMITTEE

The Committee shall:

A. Review, at least once every six months, the research facility's program, using USDA Regulations/Guide as basis.

B. Inspect, at least once every six months, all of the animal facilities, including animal study areas/satellite facilities, using USDA Regulations/Guide as basis. (USDA does not require that farm animal studies be included.)

C. Prepare reports of IACUC evaluations and submit the reports to the Institutional Official.

D. Review and investigate legitimate concerns involving the care and use of animals at the research facility resulting from public complaints and from reports of non-compliance received from facility personnel or employees.

E. Make recommendations to the Institutional Official regarding any aspect of the research facility's animal program, facilities or personnel training.

F. Review and approve, require modifications in (to secure approval), or withhold approval of those components of proposed activities related to the care and use of animals.

G. Review and approve, require modification in (to secure approval), or withhold approval of proposed significant changes regarding the care and use of animals in ongoing activities.

H. Suspend an activity involving animals when necessary; take corrective action and report to funding agency and USDA.

IV. OFFICERS

A. Chairperson – The Chairperson shall be elected annually from and by the Committee membership at the last meeting of the academic year. The Chairperson shall:

1. Preside at all meeting or designate a member to serve in his/her absence.

2. Prepare and distribute a tentative agenda to Committee members at least three working days prior to the meeting.

3. Call special meetings and appoint ad hoc subcommittees when necessary.

4. Assume responsibility for the preparation of the annual report to the Vice President for Academic Affairs in collaboration with the Executive Officer.

5. Assume responsibility of execution of Committee policies via the Executive Officer.

B. Secretary – The Secretary shall be elected annually from and by the Committee membership at the last meeting of the academic year. The Secretary shall:

1. Record the minutes of all committee meetings.

2. Assist with the preparation of the agenda.

3. Assist with the preparation of the annual report to the Vice President for Academic Affairs.

C. Executive Officer – The Executive Officer shall be the Director of Sponsored Programs and shall be appointed by the President of the University in accordance with the approved procedure for making such appointments. The Executive Officer shall:

1. Serve as the Institutional/University Officer for the Committee and as the liaison between the University, Committee, and Office for Protection from Research Risks, Division of Animal Welfare, Department of Health and Human Services.

2. Be responsible for the University's Animal Welfare Assurance.

3. Provide an annual report to the Office for Protection from Research Risks, Division of Animal Welfare, describing the activities of the Committee including any changes in membership, dates of inspection, and dates evaluations were submitted to his/her office. The Executive Officer shall obtain the appropriate University signature for all reports submitted.

4. Serve as a consultant to the Committee and provide assistance in the conduct of Committee business.

5. Provide administrative support and assistance to the Chairperson in the conduct and coordination of activities of the Committee.

6. Attend Committee meetings but without voting privileges.

7. Receive and prepare research proposals for review by the Committee.

V. MEETINGS AND ATTENDANCE

A. Meetings

1. There shall be a minimum of two meetings of the Committee each semester. Meetings shall be held in September, November, February and March/April. Special meetings may be called by the Chairperson as deemed necessary for the performance of Committee responsibilities.

2. Research proposals shall be made available to members for review prior to scheduled meetings.

3. The meeting agenda shall be approved at the beginning of each meeting.

4. A simple majority of the membership shall constitute a quorum.

B. Attendance

1. Attendance of members at Committee meetings is expected and required. If a member must be absent, notice should be given to the Chairperson or Executive Officer as soon as it is known.

2. Absence from fifty percent (50%) of regular meetings without due cause will result in a request by the Committee to the President of the University via the Executive Officer for replacement of that member.

VI. REVIEW PROCEDURES

All research and teaching activities involving animals shall submit the Animal Use Review Form (Attachment A) to the Committee via the Executive Officer. If the activity is a proposal to an outside agency, the review form and proposal must be submitted to the Executive Officer before the proposal is mailed to the sponsoring agency. The review form can be obtained from the Office of Sponsored Programs.

A. Research protocols are subject to a yearly review.

B. Teaching protocols involving animals are subject to a review every three years provided there are no major changes in the protocol.

ATTACHMENT 1 – Animal Use Review Form

ATTACHMENT 2 – Animal Use Classification

Revisions: May 19, 1993 (new).

Cross-references: Laboratory Animal Welfare Act (PL 89-544 and amendments); NIH "Guide for the Care and Use of Laboratory Animals"; USDA Regulations/Guide.