SOAR Student Profiles
Gabriella Morin
- SOAR Position: Member; President (2020-21); Alumni
- Major: Biology & Spanish
- Faculty Mentor(s): Dr. David Nelson
Current Focus: Parkinson’s Disease-associated mutations in PINK1:Parkin Mitophagy Pathway
Project Description
My project works to quantify the effect that Parkin protein mutants, such as C431S, have on a quality control mechanism for mitochondria linked to juvenile Parkinson’s disease. I perform transient transfections of EYFP-tagged Parkin wild type and mutant into Parkin-null HeLa cells and track association and dissociation rates while depolarizing the outer mitochondrial membrane