SOAR Student Profiles

Gabriella  Morin

Gabriella Morin

  • SOAR Position: Member; President (2020-21); Alumni
  • Major: Biology & Spanish
  • Faculty Mentor(s): Dr. David Nelson

Current Focus: Parkinson’s Disease-associated mutations in PINK1:Parkin Mitophagy Pathway

Project Description

My project works to quantify the effect that Parkin protein mutants, such as C431S, have on a quality control mechanism for mitochondria linked to juvenile Parkinson’s disease. I perform transient transfections of EYFP-tagged Parkin wild type and mutant into Parkin-null HeLa cells and track association and dissociation rates while depolarizing the outer mitochondrial membrane